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Amphetamines

Amphetamine, dextroamphetamine and methamphetamine, are collectively referred to as amphetamines. Their chemical properties and actions are so similar that even experienced users have difficulty knowing which drug they have taken.


Amphetamine was first marketed in the 1930s as Benzedrine in an over-the-counter inhaler to treat nasal congestion. By 1937 amphetamine was available by prescription in tablet form and was used in the treatment of the sleeping disorder narcolepsy and the behavioral syndrome called minimal brain dysfunction (MBD), which today is called Attention Deficit Hyperactivity Disorder (ADHD).


During World War II, amphetamine was widely used to keep the fighting men going; both dextroamphetamine (Dexedrine) and methamphetamine (Methedrine) became readily available.


As use of amphetamines spread, so did their abuse. Amphetamines became a cure-all for helping truckers to complete their long routes without falling asleep, for weight control, for helping athletes to perform better and train longer, and for treating mild depression. Intravenous amphetamine abuse spread among a subculture known as “speed freaks.” With experience, it became evident that the dangers of abuse of these drugs outweighed most of their therapeutic uses. Today, amphetamine is used as an aid in treating narcolepsy, some forms of depression, and Attention Deficit Hyperactivity Disorder (ADHD). Yet, due to its potential for abuse or addiction, other treatment methods are used more frequently.


BRAND NAME AMPHETAMINES: Adderall, Desoxyn, Desoxyn Gradumet, Dexedrine, Dexedrine Spansule and DestroStat.


SIGNS OF AMPHETAMINE OVERDOSE: Symptoms include restlessness, tremors, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.


WITHDRAWAL EFFECTS: depression, stomach cramps, nausea or vomiting, “the shakes,” tiredness. Amphetamine, dextroamphetamine and methamphetamine, are collectively referred to as amphetamines. Their chemical properties and actions are so similar that even experienced users have difficulty knowing which drug they have taken.


Today, amphetamine is used as an aid in treating narcolepsy, some forms of depression, and Attention Deficit Hyperactivity Disorder (ADHD). Yet, due to its potential for abuse or addiction, other treatment methods are used more frequently.


More information in the Prescription Drug Booklet.


Other Sources:

Club Drugs (National Library of Medicine)
Club drugs are group of psychoactive drugs. They act on the central nervous system and can cause changes in mood, awareness, and how you act. These drugs …


https://www.nlm.nih.gov/medlineplus/clubdrugs.html – Health Topics
Methamphetamine (National Library of Medicine)
Methamphetamine – meth for short – is a very addictive stimulant drug. It is a powder that can be made into a pill or a shiny rock (called a crystal). The powder can be eaten …


https://www.nlm.nih.gov/medlineplus/methamphetamine.html – Health Topics


Dextroamphetamine and Amphetamine
The combination of dextroamphetamine and amphetamine is used as part of a treatment program to control symptoms of attention deficit hyperactivity disorder (ADHD; …


https://www.nlm.nih.gov/medlineplus/druginfo/meds/a601234.html – Drugs and Supplements


Stimulants

Amphetamine (Dyanavel XR, Evekeo) is used as part of a treatment program to control symptoms of attention … are the same age) in adults and children. Amphetamine (Evekeo) is used to treat narcolepsy (a sleep …

https://www.nlm.nih.gov/medlineplus/druginfo/meds/a616004.html – Drugs and Supplements


Stimulants (Nemours Foundation) …

How Can I Help a Friend Who Cuts?  Amphetamines  Kids Health > For Teens > Amphetamines  Print A A A … How Can Someone Quit? Avoiding Amphetamines  What Are Amphetamines? Amphetamines are stimulants. They speed up functions in …


kidshealth.org/en/teens/amphetamines.html – External Health Links


Dextroamphetamine

Dextroamphetamine is used as part of a treatment program to control symptoms of attention deficit hyperactivity disorder ( … are the same age) in adults and children. Dextroamphetamine is also used to treat narcolepsy (a sleep …


https://www.nlm.nih.gov/medlineplus/druginfo/meds/a605027.html – Drugs and Supplements


Methamphetamine overdose:

Intoxication – amphetamines; Intoxication – uppers; Amphetamine intoxication; Uppers overdose; Overdose – methamphetamine; Crank overdose; Meth overdose; Crystal meth overdose; Speed overdose; …


https://www.nlm.nih.gov/medlineplus/ency/article/007480.htm – Medical Encyclopedia


Stimulant ADHD Medications — Methylphenidate and -Amphetamines (National Institute on Drug Abuse) and Amphetamines 


DrugFacts: Stimulant ADHD Medications: Methylphenidate and Amphetamines  Email Facebook Twitter Revised January 2014 Stimulant medications …


https://www.drugabuse.gov/…edications-methylphenidate-amphetamines – External Health Links

Substance use – stimulants


Amphetamines are drugs. They can be legal or illegal. They are legal when they are prescribed by … obesity , narcolepsy , or attention deficit hyperactivity disorder (ADHD). Amphetamines are illegal when they are used without a …


https://www.nlm.nih.gov/…/ency/patientinstructions/000792.htm – Medical Encyclopedia

By Bob Hansen January 29, 2022
Zyprexa (Olanzapine) is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder. More information/images in the Prescription Drug Brochure. When you receive Zyprexa extended-release injection, the medication is usually released slowly into your blood over a period of time. However, when you receive olanzapine extended-release injection, there is a small chance that olanzapine may be released into your blood too quickly. If this happens, you may experience a serious problem called Post-injection Delirium Sedation Syndrome (PDSS). If you develop PDSS, you may experience dizziness, confusion, difficulty thinking clearly, anxiety, irritability, aggressive behavior, weakness, slurred speech, difficulty walking, muscle stiffness or shaking, seizures, drowsiness, and coma (loss of consciousness for a period of time). You are most likely to experience these symptoms during the first 3 hours after you receive the medication. You will receive Zyprexa extended-release injection in a hospital, clinic, or another medical facility where you can receive emergency medical treatment if it is needed. You will need to remain in the facility for at least 3 hours after you receive the medication. While you are in the clinic, the medical staff will watch you closely for signs of PDSS. When you are ready to leave the facility, you will need a responsible person to be with you, and you should not drive a car or operate machinery for the rest of the day. Get emergency medical help right away if you experience any symptoms of PDSS after you leave the facility. A program has been set up to help people receive Zyprexa extended-release injection safely. You will need to register and agree to the rules of this program before you receive olanzapine extended-release injection. Your doctor, the pharmacy that dispenses your medication, and the medical facility where you receive your medication will also need to register. Ask your doctor if you have any questions about this program. For people being treated with olanzapine extended-release injection or Zyprexa injection: Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as olanzapine have an increased chance of death during treatment. Older adults with dementia may also have a greater chance of having a stroke or mini-stroke during treatment. Olanzapine injection and olanzapine extended-release injection are not approved by the Food and Drug Administration (FDA) for the treatment of behavior disorders in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is being treated with olanzapine injection or olanzapine extended-release injection. For more information visit the FDA website: http://www.fda.gov/Drugs Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with olanzapine extended-release injection and each time you receive an injection. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website to obtain the Medication Guide. extended-release injection, the medication is usually released slowly into your blood over a period of time. However, when you receive olanzapine extended-release injection, there is a small chance that olanzapine may be released into your blood too quickly. If this happens, you may experience a serious problem called Post-injection Delirium Sedation Syndrome (PDSS). If you develop PDSS, you may experience dizziness, confusion, difficulty thinking clearly, anxiety, irritability, aggressive behavior, weakness, slurred speech, difficulty walking, muscle stiffness or shaking, seizures, drowsiness, and coma (loss of consciousness for a period of time). You are most likely to experience these symptoms during the first 3 hours after you receive the medication. You will receive olanzapine extended-release injection in a hospital, clinic, or another medical facility where you can receive emergency medical treatment if it is needed. You will need to remain in the facility for at least 3 hours after you receive the medication. While you are in the clinic, the medical staff will watch you closely for signs of PDSS. When you are ready to leave the facility, you will need a responsible person to be with you, and you should not drive a car or operate machinery for the rest of the day. Get emergency medical help right away if you experience any symptoms of PDSS after you leave the facility. A program has been set up to help people receive olanzapine extended-release injection safely. You will need to register and agree to the rules of this program before you receive olanzapine extended-release injection. Your doctor, the pharmacy that dispenses your medication, and the medical facility where you receive your medication will also need to register. Ask your doctor if you have any questions about this program. For people being treated with olanzapine extended-release injection or olanzapine injection: Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as olanzapine have an increased chance of death during treatment. Older adults with dementia may also have a greater chance of having a stroke or mini-stroke during treatment. Olanzapine injection and olanzapine extended-release injection are not approved by the Food and Drug Administration (FDA) for the treatment of behavior disorders in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is being treated with olanzapine injection or olanzapine extended-release injection. For more information visit the FDA website: http://www.fda.gov/Drugs  Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with olanzapine extended-release injection and each time you receive an injection. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website to obtain the Medication Guide.
By Bob Hansen January 29, 2022
Zoloft (Sertraline) is included in the class of drugs called selective serotonin reuptake inhibitors (SSRIs). This class of drugs is used to treat depression, anxiety, and other mood disorders.
By Bob Hansen January 29, 2022
Zanaflex (Tizanidine) is a short-acting muscle relaxer. Tizanidine is used to relieve the spasms and increased muscle tone caused by multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control), stroke, or brain or spinal injury. Tizanidine is in a class of medications called skeletal muscle relaxants. It works by slowing action in the brain and nervous system to allow the muscles to relax. Tizanidine comes as a tablet and a capsule to take by mouth. It is usually taken consistently either always with or always without food two or three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tizanidine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Tizanidine capsules may be opened and sprinkled on soft foods such as applesauce. Talk to your doctor before opening the capsules because the effects of the medication, when used in this manner, may be different than when swallowing the capsule whole. The medication in the capsule is absorbed differently by the body than the medication in the tablet, so one product cannot be substituted for the other. Each time you have your prescription filled, look at the tablets or capsules in the bottle and make sure that you have received the right product. If you think you received the wrong medication, talk to your doctor or pharmacist right away. Your doctor will probably start you on a low dose of tizanidine and gradually increase your dose, depending on your response to this medication.  Do not stop taking tizanidine without talking to your doctor. If you suddenly stop taking tizanidine, your heart may beat faster and you may have increased blood pressure or tightness in your muscles. Your doctor will probably decrease your dose gradually.
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